Protein analysis

Physicochemical Properties

Innovative Technology Support Group for Life Science and Drug Discovery

Extinction Coefficient(EC)
EC
Capillary Electrophoresis
DSC
Liquid chromatography(LC)
RP-HPLC

Differential scanning calorimetry (DSC)

Test Introduction

A method of measuring the heat entry of a sample by simultaneously heating/cooling the protein sample and the reference material. It is used as a tool to evaluate the thermal stability and morphology of proteins through DSC analysis.

Sample

  • Biosimilar
  • Biobetter
  • Antibody
  • Antibody-drug conjugates
  • Recombinant protein drug
  • Toxine
  • vaccine

Analysis Process

  • Standard sample Sample
  • DSC
  • Data process

Analysis Result

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Material Mixing time(min) Tg(°C) Onset melting (°C) Tm (°C) ΔΗm (J/g) Onset crystallization(°C) Tc(°C) ΔΗc (J/g) Crystallinity%
PA66 10 60 246 261 72 235 233 70 ~36
PA66 20 56 244 260 69 233 231 68 ~35
PA66 30 57 243 259 71 233 231 66 ~36
PA66 45 53 245 256 73 238 234 59 ~37
G-PA66 10 56 241 252 97 243 239 85 ~49
G-PA66 20 57 243 254 103 245 241 94 ~52
G-PA66 30 51 226 239 69 229 222 74 ~35
G-PA66 45 50 218 236 48 227 217 38 ~24