PC1-1 : Peptide mapping

Test Introduction

Peptide mapping can be used in drug discovery and throughout the manufacturing process for quality control between batches to produce a unique ‘fingerprint’ of an individual protein and to compare this with the theoretical gene-derived amino acid sequence. Peptide mapping involves selectively cleaving the individual target protein using an appropriate enzyme and analyzing the peptide fragments obtained using LC-MS, and is to confirm/compare the structure of target proteins according to the reference protein.


  • Biosimilar
  • Biobetter
  • Antibody
  • Antibody-drug conjugates
  • Recombinant protein drug
  • Toxin
  • vaccine

Analysis Process

  • Protease Digestion
  • Peptide Map
  • De-novo sequencing
    Data interpretation

Analysis Result