Test Introduction

Peptide mapping can be used in drug discovery and throughout the manufacturing process for quality control between batches to produce a unique ‘fingerprint’ of an individual protein and to compare this with the theoretical gene-derived amino acid sequence. Peptide mapping involves selectively cleaving the individual target protein using an appropriate enzyme and analyzing the peptide fragments obtained using LC-MS, and is to confirm/compare the structure of target proteins according to the reference protein.

Sample

• Biosimilar
• Biobetter
• Antibody
• Antibody-drug conjugates
• Recombinant protein drug
• Toxin
• vaccine

Analysis Process

Analysis Result