Protein analysis
Protein
Innovative Technology Support Group for Life Science and Drug Discovery
PC3-1 : Disulfide Bridge Determination
Test Introduction
Disulfide bridge analysis by mass spectrometry, a powerful technique to help you identify and quantify disulfide bridges. Determination of
localization of disulfide bond and free sulfydryl group in target proteins using LC-MS, LC-MS/MS after enzyme/DTT treatment steps. Our
services help to detect potential mismatched or scrambled disulfide bridge forms using powerful mass spectrometric techniques.
Sample
- Biosimilar
- Biobetter
- Antibody
- Antibody-drug conjugates
- Recombinant protein drug
- Toxin
- vaccine
Analysis Process
- Protease Digestion
- LC-MS, LC-MS/MS
- Characterization of peaks and
De-novo sequencing
- Determination of S-S bonds
Analysis Result
Test Introduction
Disulfide bridge analysis by mass spectrometry, a powerful technique to help you identify and quantify disulfide bridges. Determination of localization of disulfide bond and free sulfydryl group in target proteins using LC-MS, LC-MS/MS after enzyme/DTT treatment steps. Our services help to detect potential mismatched or scrambled disulfide bridge forms using powerful mass spectrometric techniques.
Sample
- Biosimilar
- Biobetter
- Antibody
- Antibody-drug conjugates
- Recombinant protein drug
- Toxin
- vaccine
Analysis Process
- Protease Digestion
- LC-MS, LC-MS/MS
- Characterization of peaks and
De-novo sequencing - Determination of S-S bonds
Analysis Result
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